Accelerating the Throughput of Cellular Thermal Shift Assays for Mass Spectrometry-Based Proteomic Readout & Creating “Drug Fingerprints”
Time: 1:45 pm
day: Conference Day 2
Details:
- Automating CETSA workflows to enhance reproducibility and throughput and facilitate target-engagement studies
- Assessing TMT and label free methods in the context of small molecule-induced changes to protein stability
- Applying these improvements to the drug discovery pipeline and developing a protein stability-based “Drug Atlas”