Neo-substrate Discovery by Ubiquitin-Specific Proximity Labeling
Time: 3:45 pm
day: Conference Day 2
Details:
- Introducing an unbiased method to identify E3 ubiquitin ligase substrates with high specificity
- Revealing novel insights about molecular glue degraders and PROTACs by studying substrate ubiquitylation
- Leveraging information on protein ubiquitylation for informing discovery of degraders and other E3 ligase modulators
