Pocket Finding & Ligand Discovery by Chemoproteomics for Covalent Drug Discovery
- Outlining how combining fully functionalized libraries, automated protein-level enrichment, and DIA-MS provides a robust high-throughput chemoproteomic platform for proteome-wide screening of libraries
- Discover how protein level data provides convincing information for the presence of ligandable sites
- Discuss how the data informs about preferred chemotypes of electrophilic warheads for covalent drug design