Katherine Donovan
scientist Dana-Farber Cancer Institute
Katherine received her PhD in protein biochemistry in the lab of Prof. Renwick Dobson at the University of Canterbury, NZ. Her research interests are focused on exploring E3 ligase mechanism and methods of manipulation for targeted protein degradation. She set up and optimized a high throughput chemo-proteomics pipeline for the identification of degradation targets in the Fischer Lab as well as in the Center for Protein Degradation. Katherine continues to work on several projects related to ligase biology and protein degradation while also overseeing the degradation proteomics operation and the lab operations.
Seminars
Thursday 5th February 2026
Adopting Chemoproteomics Platforms to Inform Target Discovery & Drug Previously Undruggable Targets
10:00 am
- Developing a robust, high-throughput chemoproteomics platform to identify novel binding pockets, facilitate efficient target discovery, and drug orphan receptors
- Characterizing ligandable sites and binding pockets to unlock a plethora of novel target sites for hard-to-drug proteins
- Discussing data showing the unique benefit of applying chemoproteomics to transform target discovery and maximize time and cost-efficiency of R&D
